Publications
Lee J and JM Gross “Histone acetylation is required for retinal regeneration in zebrafish” – in revision
Lu F, Leach LL and JM Gross “A CRISPR-Cas9-mediated F0 screen to identify pro-regenerative genes in the zebrafish retinal pigment epithelium” – submitted (https://www.biorxiv.org/content/10.1101/2022.08.28.505611v1 ) (2022)
Bian F, Daghsni M , Lu F, Liu S, Gross JM and I Al Diri “Functional analysis of PAX6 genomic occupancy during retinogenesis reveals precise temporal and spatial utilization of transcriptional enhancers and super-enhancers” – Development - 149(15):dev200642 (2022)
Leach LL, Fisher GB, Gross JM. Nitroreductase/Metronidazole-Mediated Ablation and a MATLAB Platform (RpEGEN) for Studying Regeneration of the Zebrafish Retinal Pigment Epithelium. J Vis Exp. (181):10.3791/63658 (2022)
Lu F, Leach LL and JM Gross “mTOR signaling modulates innate immune system activity required for pigment epithelium regeneration in zebrafish” – PloS Genetics – 18(3):e1009628 (2022)
Kingston R, Amin D, Misra S, Gross JM and T Kuwajima “The Serotonin Transporter Is a Regulator of Neurodegeneration and Axon Regeneration After Retinal Injury” – PLoS Genetics – 17(11):e1009885 (2021)
Chen S, Lathrop K, Kuwajima T and JM Gross “Retinal ganglion cell survival after severe optic nerve injury is modulated by crosstalk between JAK/STAT signaling and innate immune responses in the zebrafish retina" Development - 149(8):dev199694 (2021)
George S, Lu F, Rao M, Leach LL and JM Gross “The Retinal Pigment Epithelium: Development, Injury Responses and Regenerative Potential in Mammalian and non-Mammalian Systems” – Progress in Retina and Eye Research – 100969. doi: 10.1016/j.preteyeres.2021.100969 (2021)
Leach LL, George S, Gabriel A and JM Gross “Innate immune system activity is a critical regulator of retinal pigment epithelium regeneration in zebrafish” – PNAS - 118(21):e2017198118 (2021)
Raeisossadati R, Ferrari MFR, Kihara AH, Al Diri I and JM Gross “Epigenetic regulation of retinal development” Epigenetics and Chromatin 14:11 (2021) [PDF]
Koenig K and JM Gross “Evolution and Development of Complex Eyes: A Celebration of Diversity” – Development 147: dev182923 doi: 10.1242/dev.182923 (2020) [PDF]
Angileri K and JM Gross “dnmt1 function is required to maintain retinal stem cells within the ciliary marginal zone of the zebrafish eye” – Scientific Reports – 10(1):11293 (2020) [PDF]
Sinagoga K, Larimer-Picciani A, George S, Spencer SA, Lister JA and JM Gross “Mitf-family transcription factor function is required within cranial neural crest cells to promote choroid fissure closure” – Development – 147(21):dev187047 (2020) [PDF]
Taler K, Weiss O, Rubinstein A, Seritrakul P, Gross JM and A Inbal “Lysyl hydroxylase 3 is required to maintain integrity and fate of lens epithelium” – Developmental Biology – 458 (2), 177-188 (2020) [PDF]
Gath N and JM Gross. “Zebrafish mab21l2 mutants possess severe defects in optic cup morphogenesis, lens and cornea development.” Developmental Dynamics 248(7):514-529 (2019) [PDF]
Seritrakul P and JM Gross “Genetic and epigenetic control of retinal development in Zebrafish” Current Opinion in Neurobiology – 59:120-127 (2019) [PDF]
Hanovice N, Leach LL, Slater K, Gabriel AE, Romanovicz D, Shao E, Collery R, Burton EA, Lathrop K, Link BA and JM Gross “Regeneration of the zebrafish retinal pigment epithelium after widespread genetic ablation” – PLoS Genetics – 15(1):e1007939 (2019) [PDF]
Hanovice NJ, McMains E, Gross JM “Using GAL4-Inducible Transgenics to Modulate Rho GTPase Activity in Zebrafish” Methods Mol Biol 1821:359-370 (2018)
Bernstein CS, Anderson MT, Gohel C, Slater K, Gross JM and S Agarwala “The Cellular bases of choroid fissure formation and closure” – Developmental Biology 440(2):137-151 (2018) [PDF]
Siddam AD, Gautier-Courteille C, Perez-Campos L, Anand D, Kakrana A, Dang CA, Legagneux V, Méreau A, Viet J, Gross JM, Paillard L, Lachke SA "The RNA-binding protein Celf1 post-transcriptionally regulates p27Kip1 and Dnase2b to control fiber cell nuclear degradation in lens development" PLoS Genetics - 14(3):e1007278 (2018) [PDF]
Seritrakul P and JM Gross "Tet-mediated DNA hydroxymethylation regulates retinal neurogenesis by modulating cell-extrinsic signaling pathways" PLoS Genetics - 13(9):e1006987 (2017) [PDF]
Johnston JJ. Wentzensen IM, Crenshaw M, Sapp JC, Lee C, Gross JM, Wallingford JB and LG Biesecker “Compound Heterozygous Alterations in Intraflagellar Transport Protein CLUAP1 in a Child with Joubert Syndrome” Cold Spring Harb Mol Case Stud. Jul 5;3(4) (2017)
James A, Lee C, Williams AM, Angileri K, Lathrop K, and JM Gross "The hyaloid vasculature facilitates basement membrane breakdown during choroid fissure closure in the zebrafish eye." Developmental Biology - 419(2):262-272 (2016) [PDF]
Koenig K, Sun P, Meyer E, JM Gross “Cell Fate Determination During Eye Development in the Cephalopod Doryteuthis pealeii” Development Sep 1;143(17):3168-81. (2016) [PDF]
Hanovice NJ, McMains E and JM Gross “A GAL4-inducible transgenic toolkit for the in vivo modulation of Rho GTPase activity in zebrafish” Developmental Dynamics – Aug;245(8):844-53. (2016) [PDF]
Hanovice N, Daly CMS and JM Gross “N-ethylmaleimide-sensitive factor b (nsfb) is required for normal pigmentation of the zebrafish retinal pigmented epithelium” Investigative Ophthalmology and Visual Science – Nov 1;56(12):7535-44 (2015) [PDF]
Hartsock A, Arnold V, Lee C and JM Gross “In Vivo Analysis of Hyaloid Vasculature Morphogenesis in Zebrafish: A role for the lens in maturation and maintenance of the hyaloid” – Developmental Biology – 394(2):327-39 (2014) [PDF]
Lee C, JB Wallingford and JM Gross – “Mutation in cluap1/qilin results in photoreceptor degeneration in zebrafish” – Investigative Ophthalmology and Visual Science – 55(7):4585-4592 (2014) [PDF]
Seritrakul P and JM Gross “Expression of the de novo DNA Methyltransferases (dnmt3-dnmt8) during zebrafish lens development” - Developmental Dynamics - Feb;243(2):350-6 (2014) [PDF]
Shine L, Kilty C, Gross JM, and B Kennedy “Vacuolar ATPases and their role in vision” in Retinal Degeneration 2013 (2014)
Daly CMS, Willer J, Gregg RG and JM Gross “snow white, a zebrafish model of Hermansky-Pudlak Syndrome Type 5” Genetics Oct;195(2):481-94. (2013) [PDF]
Lee J, Lee BK and JM Gross “Bcl6a function is required during optic cup formation to prevent p53-dependent apoptosis and colobomata” Human Molecular Genetics Sep 1;22(17):3568-82 (2013) [PDF]
Lee J, Cox BD, Daly C, Lee C, Nuckels RJ, Tittle RK, Uribe RA and JM Gross “An ENU mutagenesis screen in zebrafish for visual system mutants identifies a novel splice-acceptor site mutation in patched2 that results in colobomas” Investigative Ophthalmology and Visual Science – 53(13):8214-21 (2012) [PDF]
Hayes J, Hartsock A, Napier H, Link BA and JM Gross “Integrin alpha5/Fibronectin and Focal adhesion kinase are required for normal lens development in zebrafish” – Molecular Biology of the Cell – 23(24) 4725-38 (2012) [PDF]
Luo J, Uribe RA, Hayton S, Calinescu A, Gross JM, PF Hitchcock “Midkine-A functions upstream of Id2a to regulate cell cycle kinetics in the developing vertebrate retina” Neural Development - 7(1):33 (2012) [PDF]
Uribe RA, Kwon T, Marcotte EM, JM Gross "Id2a functions to limit Notch pathway activity and thereby influence the transition from proliferation to differentiation of retinoblasts during zebrafish retinogenesis"– Developmental Biology, 371, 280-292 (2012) [PDF]
Bibliowicz J and JM Gross “Progenitor overproliferation, ectopic neuronal differentiation and retinal dysplasia in a zebrafish model of Basal Cell Naevus Syndrome” – Investigative Ophthalmology and Visual Science – 52(12):8868-77 (2011) [PDF]
Bibliowicz J, Tittle RK and JM Gross “Towards a better understanding of human eye disease: insights from the zebrafish, Danio rerio” in “Animal models of Human diseases" in the review series "Progress in Nucleic Acid Research and Molecular Biology", Kyung-Tai Min and Karen Chang, ed. Elsevier Press (2011) [PDF]
Tittle RK, Sze R, Ng A, Nuckels RJ, Swartz ME, Anderson RM, Bosch J, Stainier DYR, Eberhart JK and JM Gross. "Uhrf1 and Dnmt1 are required for development and maintenance of the zebrafish lens." Developmental Biology 350: 50-63 (2011). [PDF]
Uribe RA and JM Gross. "Id2A influences neuron and glia formation in the zebrafish retina by modulating retinoblast cell cycle kinetics." Development 137: 3763-3774 (2010). [PDF]
Bibliowicz J and JM Gross. "Expanded progenitor populations, vitreo-retinal abnormalities, and Muller glial reactivity in the zebrafish leprechaun/patched2 retina." BMC Developmental Biology 9:52 (2009). [PDF]
Ng A, Uribe RA, Yieh L, Nuckels R and JM Gross. "Zebrafish mutations in gart and paics identify crucial roles for de novo purine synthesis in vertebrate pigmentation and ocular development." Development 136(15): 2601-2611 (2009). [PDF]
Brown JD, Dutta S, Bharti K, Bonner RF, Munson PJ, Dawid IB, Akhtar AL, Onojafe IF, Alur RP, Gross JM, Hejtmancik JF, Jiao X, Chan WY and BP Brooks. "Expression profiling during ocular development identifies 2 Nlz genes with a critical role in optic fissure closure." Proceedings of the National Academy of Sciences 105(5): 1462-1467 (2009). [PDF]
Nuckels RJ, Ng A, Darland T and JM Gross. "The Vacuolar-ATPase Complex Regulates Retinoblast Proliferation and Survival, Photoreceptor Morphogenesis and Pigmentation in the Zebrafish Eye." Investigative Ophthalmology and Visual Science 50(2): 893-905 (2009). [PDF]
Lee J, Willer J, Willer GB, Smith K, Gregg R and JM Gross. "Zebrafish blowout provides genetic evidence for Patched1-mediated negative regulation of Hedgehog signaling within the proximal optic vesicle of the vertebrate eye." Developmental Biology 319(1): 10-22 (2008). [PDF]
Gross JM and BD Perkins. "Zebrafish mutants as models for congenital ocular disorders in humans." Molecular Reproduction and Development 75(3): 547-555 (2008). [PDF]
Nuckels RJ and JM Gross. "Histological preparation of embryonic and adult zebrafish eyes ." Cold Spring Harbor Protocols doi:10.1101/pdb.prot4846 (2007) [PDF]
Uribe RA and JM Gross. "Immunohistochemistry on cryosections from embryonic and adult zebrafish eyes." Cold Spring Harbor Protocols doi:10.1101/pdb.prot4779 (2007). [PDF]
Lee J and JM Gross. "Laminin Beta 1 and Gamma 1 Containing Laminins are Essential for Basement Membrane Integrity in the Zebrafish Eye." Investigative Ophthalmology and Visual Science 48, 2483-2490 (2007). [PDF]
Fairbank PD, Lee C, Ellis A, Hildebrand JD, Gross JM, and JB Wallingford. "Shroom2 (APXL) regulates melanosome biogenesis and localization in the retinal pigment epithelium." Development 133(20), 4109-4118 (2006). [PDF]
Lu F, Leach LL and JM Gross “A CRISPR-Cas9-mediated F0 screen to identify pro-regenerative genes in the zebrafish retinal pigment epithelium” – submitted (https://www.biorxiv.org/content/10.1101/2022.08.28.505611v1 ) (2022)
Bian F, Daghsni M , Lu F, Liu S, Gross JM and I Al Diri “Functional analysis of PAX6 genomic occupancy during retinogenesis reveals precise temporal and spatial utilization of transcriptional enhancers and super-enhancers” – Development - 149(15):dev200642 (2022)
Leach LL, Fisher GB, Gross JM. Nitroreductase/Metronidazole-Mediated Ablation and a MATLAB Platform (RpEGEN) for Studying Regeneration of the Zebrafish Retinal Pigment Epithelium. J Vis Exp. (181):10.3791/63658 (2022)
Lu F, Leach LL and JM Gross “mTOR signaling modulates innate immune system activity required for pigment epithelium regeneration in zebrafish” – PloS Genetics – 18(3):e1009628 (2022)
Kingston R, Amin D, Misra S, Gross JM and T Kuwajima “The Serotonin Transporter Is a Regulator of Neurodegeneration and Axon Regeneration After Retinal Injury” – PLoS Genetics – 17(11):e1009885 (2021)
Chen S, Lathrop K, Kuwajima T and JM Gross “Retinal ganglion cell survival after severe optic nerve injury is modulated by crosstalk between JAK/STAT signaling and innate immune responses in the zebrafish retina" Development - 149(8):dev199694 (2021)
George S, Lu F, Rao M, Leach LL and JM Gross “The Retinal Pigment Epithelium: Development, Injury Responses and Regenerative Potential in Mammalian and non-Mammalian Systems” – Progress in Retina and Eye Research – 100969. doi: 10.1016/j.preteyeres.2021.100969 (2021)
Leach LL, George S, Gabriel A and JM Gross “Innate immune system activity is a critical regulator of retinal pigment epithelium regeneration in zebrafish” – PNAS - 118(21):e2017198118 (2021)
Raeisossadati R, Ferrari MFR, Kihara AH, Al Diri I and JM Gross “Epigenetic regulation of retinal development” Epigenetics and Chromatin 14:11 (2021) [PDF]
Koenig K and JM Gross “Evolution and Development of Complex Eyes: A Celebration of Diversity” – Development 147: dev182923 doi: 10.1242/dev.182923 (2020) [PDF]
Angileri K and JM Gross “dnmt1 function is required to maintain retinal stem cells within the ciliary marginal zone of the zebrafish eye” – Scientific Reports – 10(1):11293 (2020) [PDF]
Sinagoga K, Larimer-Picciani A, George S, Spencer SA, Lister JA and JM Gross “Mitf-family transcription factor function is required within cranial neural crest cells to promote choroid fissure closure” – Development – 147(21):dev187047 (2020) [PDF]
Taler K, Weiss O, Rubinstein A, Seritrakul P, Gross JM and A Inbal “Lysyl hydroxylase 3 is required to maintain integrity and fate of lens epithelium” – Developmental Biology – 458 (2), 177-188 (2020) [PDF]
Gath N and JM Gross. “Zebrafish mab21l2 mutants possess severe defects in optic cup morphogenesis, lens and cornea development.” Developmental Dynamics 248(7):514-529 (2019) [PDF]
Seritrakul P and JM Gross “Genetic and epigenetic control of retinal development in Zebrafish” Current Opinion in Neurobiology – 59:120-127 (2019) [PDF]
Hanovice N, Leach LL, Slater K, Gabriel AE, Romanovicz D, Shao E, Collery R, Burton EA, Lathrop K, Link BA and JM Gross “Regeneration of the zebrafish retinal pigment epithelium after widespread genetic ablation” – PLoS Genetics – 15(1):e1007939 (2019) [PDF]
Hanovice NJ, McMains E, Gross JM “Using GAL4-Inducible Transgenics to Modulate Rho GTPase Activity in Zebrafish” Methods Mol Biol 1821:359-370 (2018)
Bernstein CS, Anderson MT, Gohel C, Slater K, Gross JM and S Agarwala “The Cellular bases of choroid fissure formation and closure” – Developmental Biology 440(2):137-151 (2018) [PDF]
Siddam AD, Gautier-Courteille C, Perez-Campos L, Anand D, Kakrana A, Dang CA, Legagneux V, Méreau A, Viet J, Gross JM, Paillard L, Lachke SA "The RNA-binding protein Celf1 post-transcriptionally regulates p27Kip1 and Dnase2b to control fiber cell nuclear degradation in lens development" PLoS Genetics - 14(3):e1007278 (2018) [PDF]
Seritrakul P and JM Gross "Tet-mediated DNA hydroxymethylation regulates retinal neurogenesis by modulating cell-extrinsic signaling pathways" PLoS Genetics - 13(9):e1006987 (2017) [PDF]
Johnston JJ. Wentzensen IM, Crenshaw M, Sapp JC, Lee C, Gross JM, Wallingford JB and LG Biesecker “Compound Heterozygous Alterations in Intraflagellar Transport Protein CLUAP1 in a Child with Joubert Syndrome” Cold Spring Harb Mol Case Stud. Jul 5;3(4) (2017)
James A, Lee C, Williams AM, Angileri K, Lathrop K, and JM Gross "The hyaloid vasculature facilitates basement membrane breakdown during choroid fissure closure in the zebrafish eye." Developmental Biology - 419(2):262-272 (2016) [PDF]
Koenig K, Sun P, Meyer E, JM Gross “Cell Fate Determination During Eye Development in the Cephalopod Doryteuthis pealeii” Development Sep 1;143(17):3168-81. (2016) [PDF]
Hanovice NJ, McMains E and JM Gross “A GAL4-inducible transgenic toolkit for the in vivo modulation of Rho GTPase activity in zebrafish” Developmental Dynamics – Aug;245(8):844-53. (2016) [PDF]
Hanovice N, Daly CMS and JM Gross “N-ethylmaleimide-sensitive factor b (nsfb) is required for normal pigmentation of the zebrafish retinal pigmented epithelium” Investigative Ophthalmology and Visual Science – Nov 1;56(12):7535-44 (2015) [PDF]
Hartsock A, Arnold V, Lee C and JM Gross “In Vivo Analysis of Hyaloid Vasculature Morphogenesis in Zebrafish: A role for the lens in maturation and maintenance of the hyaloid” – Developmental Biology – 394(2):327-39 (2014) [PDF]
Lee C, JB Wallingford and JM Gross – “Mutation in cluap1/qilin results in photoreceptor degeneration in zebrafish” – Investigative Ophthalmology and Visual Science – 55(7):4585-4592 (2014) [PDF]
Seritrakul P and JM Gross “Expression of the de novo DNA Methyltransferases (dnmt3-dnmt8) during zebrafish lens development” - Developmental Dynamics - Feb;243(2):350-6 (2014) [PDF]
Shine L, Kilty C, Gross JM, and B Kennedy “Vacuolar ATPases and their role in vision” in Retinal Degeneration 2013 (2014)
Daly CMS, Willer J, Gregg RG and JM Gross “snow white, a zebrafish model of Hermansky-Pudlak Syndrome Type 5” Genetics Oct;195(2):481-94. (2013) [PDF]
Lee J, Lee BK and JM Gross “Bcl6a function is required during optic cup formation to prevent p53-dependent apoptosis and colobomata” Human Molecular Genetics Sep 1;22(17):3568-82 (2013) [PDF]
Lee J, Cox BD, Daly C, Lee C, Nuckels RJ, Tittle RK, Uribe RA and JM Gross “An ENU mutagenesis screen in zebrafish for visual system mutants identifies a novel splice-acceptor site mutation in patched2 that results in colobomas” Investigative Ophthalmology and Visual Science – 53(13):8214-21 (2012) [PDF]
Hayes J, Hartsock A, Napier H, Link BA and JM Gross “Integrin alpha5/Fibronectin and Focal adhesion kinase are required for normal lens development in zebrafish” – Molecular Biology of the Cell – 23(24) 4725-38 (2012) [PDF]
Luo J, Uribe RA, Hayton S, Calinescu A, Gross JM, PF Hitchcock “Midkine-A functions upstream of Id2a to regulate cell cycle kinetics in the developing vertebrate retina” Neural Development - 7(1):33 (2012) [PDF]
Uribe RA, Kwon T, Marcotte EM, JM Gross "Id2a functions to limit Notch pathway activity and thereby influence the transition from proliferation to differentiation of retinoblasts during zebrafish retinogenesis"– Developmental Biology, 371, 280-292 (2012) [PDF]
Bibliowicz J and JM Gross “Progenitor overproliferation, ectopic neuronal differentiation and retinal dysplasia in a zebrafish model of Basal Cell Naevus Syndrome” – Investigative Ophthalmology and Visual Science – 52(12):8868-77 (2011) [PDF]
Bibliowicz J, Tittle RK and JM Gross “Towards a better understanding of human eye disease: insights from the zebrafish, Danio rerio” in “Animal models of Human diseases" in the review series "Progress in Nucleic Acid Research and Molecular Biology", Kyung-Tai Min and Karen Chang, ed. Elsevier Press (2011) [PDF]
Tittle RK, Sze R, Ng A, Nuckels RJ, Swartz ME, Anderson RM, Bosch J, Stainier DYR, Eberhart JK and JM Gross. "Uhrf1 and Dnmt1 are required for development and maintenance of the zebrafish lens." Developmental Biology 350: 50-63 (2011). [PDF]
Uribe RA and JM Gross. "Id2A influences neuron and glia formation in the zebrafish retina by modulating retinoblast cell cycle kinetics." Development 137: 3763-3774 (2010). [PDF]
Bibliowicz J and JM Gross. "Expanded progenitor populations, vitreo-retinal abnormalities, and Muller glial reactivity in the zebrafish leprechaun/patched2 retina." BMC Developmental Biology 9:52 (2009). [PDF]
Ng A, Uribe RA, Yieh L, Nuckels R and JM Gross. "Zebrafish mutations in gart and paics identify crucial roles for de novo purine synthesis in vertebrate pigmentation and ocular development." Development 136(15): 2601-2611 (2009). [PDF]
Brown JD, Dutta S, Bharti K, Bonner RF, Munson PJ, Dawid IB, Akhtar AL, Onojafe IF, Alur RP, Gross JM, Hejtmancik JF, Jiao X, Chan WY and BP Brooks. "Expression profiling during ocular development identifies 2 Nlz genes with a critical role in optic fissure closure." Proceedings of the National Academy of Sciences 105(5): 1462-1467 (2009). [PDF]
Nuckels RJ, Ng A, Darland T and JM Gross. "The Vacuolar-ATPase Complex Regulates Retinoblast Proliferation and Survival, Photoreceptor Morphogenesis and Pigmentation in the Zebrafish Eye." Investigative Ophthalmology and Visual Science 50(2): 893-905 (2009). [PDF]
Lee J, Willer J, Willer GB, Smith K, Gregg R and JM Gross. "Zebrafish blowout provides genetic evidence for Patched1-mediated negative regulation of Hedgehog signaling within the proximal optic vesicle of the vertebrate eye." Developmental Biology 319(1): 10-22 (2008). [PDF]
Gross JM and BD Perkins. "Zebrafish mutants as models for congenital ocular disorders in humans." Molecular Reproduction and Development 75(3): 547-555 (2008). [PDF]
Nuckels RJ and JM Gross. "Histological preparation of embryonic and adult zebrafish eyes ." Cold Spring Harbor Protocols doi:10.1101/pdb.prot4846 (2007) [PDF]
Uribe RA and JM Gross. "Immunohistochemistry on cryosections from embryonic and adult zebrafish eyes." Cold Spring Harbor Protocols doi:10.1101/pdb.prot4779 (2007). [PDF]
Lee J and JM Gross. "Laminin Beta 1 and Gamma 1 Containing Laminins are Essential for Basement Membrane Integrity in the Zebrafish Eye." Investigative Ophthalmology and Visual Science 48, 2483-2490 (2007). [PDF]
Fairbank PD, Lee C, Ellis A, Hildebrand JD, Gross JM, and JB Wallingford. "Shroom2 (APXL) regulates melanosome biogenesis and localization in the retinal pigment epithelium." Development 133(20), 4109-4118 (2006). [PDF]
